Selective Serotonin Reuptake Inhibitor

SSRI

clinical

Updated 5/16/2026

Definition

Pharmacological drug class code (SSRI) assigned in pharmacy benefit management and EHR medication databases to antidepressants that inhibit serotonin reabsorption (e.g., fluoxetine, sertraline). Used in drug utilization review, formulary tier assignment, and clinical decision support rules to monitor mental health treatment patterns and flag drug-drug interactions in claims and pharmacy dispensing systems.

Standard Abbreviation

SSRI

Database Usage

-- Example column naming
CREATE TABLE claims (
  clm_id VARCHAR(50),
  ssri VARCHAR(100),  -- Selective Serotonin Reuptake Inhibitor (max 100 chars)
  ...
);

-- Example in SELECT
SELECT
  clm_id,
  ssri as selective_serotonin_reuptake_inhibitor
FROM claims;

Common uses in healthcare data

Risk stratification and population health analytics
CMS-HCC risk adjustment and RAF score calculation
Quality measure attribution and HEDIS reporting
Clinical data warehouse schema design
Value-based care contract performance tracking

Example database column name

ISO-11179 snake_case standard

-- Recommended column name
ssri

-- Example DDL
CREATE TABLE healthcare_data (
  record_id   VARCHAR(50)   NOT NULL,
  ssri         VARCHAR(100),  -- Selective Serotonin Reuptake Inhibitor (max 100 chars)
  created_dt  TIMESTAMP     NOT NULL DEFAULT NOW()
);

Column names follow the ISO-11179 naming convention: lowercase, underscore-separated, using the standard abbreviation as a prefix where applicable.

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